ADB-INACA
ADB-INACA
$2850.00$2650.00
First detected in the United States in November 2022.
A precursor to several synthetic cannabinoids, and may coelute with finished product, creating analytical challenges.
ADB-INACA is a precursor to several synthetic cannabinoids, as shown below.

A New Synthetic Cannabinoid or Coelution?
ADB-INACA may coelute with the finished product, creating an analytical challenge. Starting in late 2022, Cayman received requests for assistance identifying a new synthetic cannabinoid. These unknowns were submitted from agencies in Texas, Arkansas, Pennsylvania, Kentucky, Illinois, and Turkey.
Based on the mass spectra, we noticed several similarities with ADB-BUTINACA and ADB-INACA. We concluded that it was possible ADB-INACA was coeluting with ADB-BUTINACA.
Due to the number and frequency of unknown requests and several inquiries on methods to help differentiate them, our ISO department developed a GC method for the separation of ADB-BUTINACA from its precursor ADB-INACA.
Bis-Alkylated Byproducts
MDMB-INACA can also form bis-alkylated byproducts that may be encountered in casework. MDMB-INACA is typically reacted with a base to add the tail piece group. If the base is strong, it may hydrolyze the methyl ester, yielding the acid product. Hence, the tail piece group is added not only to the indazole nitrogen but also to the acid group, resulting in the bis-alkylated byproducts 4en-PDMB-4en-PINACA and 5F-PDMB-5F-PINACA.

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